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Requirement of Translation But Not Transcription for the Maintenance of Long-Term Depression in the CA1 Region of Freely Moving Rats

Hippocampal long-term depression (LTD) comprises a persistent reduction in synaptic strength that can be induced in the CA1 region by repeated low-frequency stimulation (LFS). Previous studies have demonstrated that hippocampal long-term potentiation requires de novo protein synthesis. Whether hippo...

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Détails bibliographiques
Publié dans:J Neurosci
Auteurs principaux: Manahan-Vaughan, Denise, Kulla, Alexander, Frey, J. Uwe
Format: Artigo
Langue:Inglês
Publié: Society for Neuroscience 2000
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6773181/
https://ncbi.nlm.nih.gov/pubmed/11069965
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.20-22-08572.2000
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