Loss of Presynaptic and Postsynaptic Structures Is Accompanied by Compensatory Increase in Action Potential-Dependent Synaptic Input to Layer V Neocortical Pyramidal Neurons in Aged Rats

Reduction in both presynaptic and postsynaptic structures in the aging neocortex may significantly affect functional synaptic properties in this area. To directly address this issue, we combined whole-cell patch-clamp recording of spontaneously occurring postsynaptic currents (PSCs) with morphologic...

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Bibliografski detalji
Izdano u:J Neurosci
Glavni autori: Wong, Tak Pan, Marchese, Giorgio, Casu, Maria Antonietta, Ribeiro-da-Silva, Alfredo, Cuello, A. Claudio, De Koninck, Yves
Format: Artigo
Jezik:Inglês
Izdano: Society for Neuroscience 2000
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ARTICLE
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6773180/
https://ncbi.nlm.nih.gov/pubmed/11069968
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.20-22-08596.2000
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