Loss of Presynaptic and Postsynaptic Structures Is Accompanied by Compensatory Increase in Action Potential-Dependent Synaptic Input to Layer V Neocortical Pyramidal Neurons in Aged Rats

Reduction in both presynaptic and postsynaptic structures in the aging neocortex may significantly affect functional synaptic properties in this area. To directly address this issue, we combined whole-cell patch-clamp recording of spontaneously occurring postsynaptic currents (PSCs) with morphologic...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Wong, Tak Pan, Marchese, Giorgio, Casu, Maria Antonietta, Ribeiro-da-Silva, Alfredo, Cuello, A. Claudio, De Koninck, Yves
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2000
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ARTICLE
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6773180/
https://ncbi.nlm.nih.gov/pubmed/11069968
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.20-22-08596.2000
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