D(2) Dopamine Receptors in Striatal Medium Spiny Neurons Reduce L-Type Ca(2+) Currents and Excitability via a Novel PLCβ1–IP(3)–Calcineurin-Signaling Cascade

In spite of the recognition that striatal D(2) receptors are critical determinants in a variety of psychomotor disorders, the cellular mechanisms by which these receptors shape neuronal activity have remained a mystery. The studies presented here reveal that D(2) receptor stimulation in enkephalin-e...

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Publicat a:J Neurosci
Autors principals: Hernández-López, Salvador, Tkatch, Tatiana, Perez-Garci, Enrique, Galarraga, Elvira, Bargas, José, Hamm, Heidi, Surmeier, D. James
Format: Artigo
Idioma:Inglês
Publicat: Society for Neuroscience 2000
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6773013/
https://ncbi.nlm.nih.gov/pubmed/11124974
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.20-24-08987.2000
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