Impaired Fast-Spiking, Suppressed Cortical Inhibition, and Increased Susceptibility to Seizures in Mice Lacking Kv3.2 K(+) Channel Proteins

Voltage-gated K(+) channels of the Kv3 subfamily have unusual electrophysiological properties, including activation at very depolarized voltages (positive to −10 mV) and very fast deactivation rates, suggesting special roles in neuronal excitability. In the brain, Kv3 channels are prominently expres...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Lau, David, de Miera, Eleazar Vega-Saenz, Contreras, Diego, Ozaita, Ander, Harvey, Michael, Chow, Alan, Noebels, Jeffrey L., Paylor, Richard, Morgan, James I., Leonard, Christopher S., Rudy, Bernardo
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2000
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ARTICLE
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6773003/
https://ncbi.nlm.nih.gov/pubmed/11124984
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.20-24-09071.2000
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