Impaired Synaptic Plasticity and cAMP Response Element-Binding Protein Activation in Ca(2+)/Calmodulin-Dependent Protein Kinase Type IV/Gr-Deficient Mice

The Ca(2+)/calmodulin-dependent protein kinase type IV/Gr (CaMKIV/Gr) is a key effector of neuronal Ca(2+) signaling; its function was analyzed by targeted gene disruption in mice. CaMKIV/Gr-deficient mice exhibited impaired neuronal cAMP-responsive element binding protein (CREB) phosphorylation and...

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Publicado no:J Neurosci
Main Authors: Ho, Nga, Liauw, Jason A., Blaeser, Frank, Wei, Feng, Hanissian, Silva, Muglia, Lisa M., Wozniak, David F., Nardi, Anthony, Arvin, Kara L., Holtzman, David M., Linden, David J., Zhuo, Min, Muglia, Louis J., Chatila, Talal A.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2000
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ARTICLE
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6772951/
https://ncbi.nlm.nih.gov/pubmed/10964952
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.20-17-06459.2000
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