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Impaired Synaptic Plasticity and cAMP Response Element-Binding Protein Activation in Ca(2+)/Calmodulin-Dependent Protein Kinase Type IV/Gr-Deficient Mice

The Ca(2+)/calmodulin-dependent protein kinase type IV/Gr (CaMKIV/Gr) is a key effector of neuronal Ca(2+) signaling; its function was analyzed by targeted gene disruption in mice. CaMKIV/Gr-deficient mice exhibited impaired neuronal cAMP-responsive element binding protein (CREB) phosphorylation and...

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Bibliografske podrobnosti
izdano v:J Neurosci
Main Authors: Ho, Nga, Liauw, Jason A., Blaeser, Frank, Wei, Feng, Hanissian, Silva, Muglia, Lisa M., Wozniak, David F., Nardi, Anthony, Arvin, Kara L., Holtzman, David M., Linden, David J., Zhuo, Min, Muglia, Louis J., Chatila, Talal A.
Format: Artigo
Jezik:Inglês
Izdano: Society for Neuroscience 2000
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Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6772951/
https://ncbi.nlm.nih.gov/pubmed/10964952
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.20-17-06459.2000
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