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Differential cAMP Gating of Glutamatergic Signaling Regulates Long-Term State Changes in the Suprachiasmatic Circadian Clock

We investigated a role for cAMP/protein kinase A (PKA) in light/glutamate (GLU)-stimulated state changes of the mammalian circadian clock in the suprachiasmatic nucleus (SCN). Nocturnal GLU treatment elevated [cAMP]; however, agonists of cAMP/PKA did not mimic the effects of light/GLU. Coincident ac...

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Pubblicato in:J Neurosci
Autori principali: Tischkau, Shelley A., Gallman, Eve A., Buchanan, Gordon F., Gillette, Martha U.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Society for Neuroscience 2000
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6772885/
https://ncbi.nlm.nih.gov/pubmed/11027248
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.20-20-07830.2000
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