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Deficiency of Complement Defense Protein CD59 May Contribute to Neurodegeneration in Alzheimer's Disease

Complement defense 59 (CD59) is a cell surface glycophosphoinositol (GPI)-anchored protein that prevents complement membrane attack complex (MAC) assembly. Here, we present evidence from ELISA assays that CD59 protein levels are significantly decreased in the frontal cortex and hippocampus of Alzhei...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Yang, Li-Bang, Li, Rena, Meri, Seppo, Rogers, Joseph, Shen, Yong
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2000
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6772855/
https://ncbi.nlm.nih.gov/pubmed/11027207
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.20-20-07505.2000
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