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Deficit of Striatal Parvalbumin-Reactive GABAergic Interneurons and Decreased Basal Ganglia Output in a Genetic Rodent Model of Idiopathic Paroxysmal Dystonia

The underlying mechanisms of various types of hereditary dystonia, a common movement disorder, are still unknown. Recent findings in a genetic model of a type of paroxysmal dystonia, thedt(sz) mutant hamster, pointed to striatal dysfunctions. In the present study, immunhistochemical experiments demo...

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Publicado en:J Neurosci
Autores principales: Gernert, Manuela, Hamann, Melanie, Bennay, Mustapha, Löscher, Wolfgang, Richter, Angelika
Formato: Artigo
Lenguaje:Inglês
Publicado: Society for Neuroscience 2000
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6772842/
https://ncbi.nlm.nih.gov/pubmed/10995851
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.20-18-07052.2000
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