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IFNγ Enhances Microglial Reactions to Hippocampal Axonal Degeneration

Glial reactivity is implicated in CNS repair and regenerative responses. Microglia, the cells responding earliest to axonal injury, produce tumor necrosis factor-α (TNFα), a cytokine with both cytopathic and neuroprotective effects. We have studied activation of hippocampal microglia to produce TNFα...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Jensen, Michael B., Hegelund, Iørn V., Lomholt, Nina D., Finsen, Bente, Owens, Trevor
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2000
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6772678/
https://ncbi.nlm.nih.gov/pubmed/10804203
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.20-10-03612.2000
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