Novel Role for the NMDA Receptor Redox Modulatory Site in the Pathophysiology of Seizures

Redox-active compounds modulate NMDA receptors (NMDARs) such that reduction of NMDAR redox sites increases, and oxidation decreases, NMDAR-mediated activity. Because NMDARs contribute to the pathophysiology of seizures, redox-active compounds also may modulate seizure activity. We report that the ox...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Sanchez, Russell M., Wang, Carl, Gardner, Ginger, Orlando, Lianna, Tauck, David L., Rosenberg, Paul A., Aizenman, Elias, Jensen, Frances E.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2000
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ARTICLE
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6772486/
https://ncbi.nlm.nih.gov/pubmed/10704515
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.20-06-02409.2000
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