Ca(2+)-Evoked Serotonin Secretion by Parafollicular Cells: Roles in Signal Transduction of Phosphatidylinositol 3′-kinase, and the γ and ζ Isoforms of Protein Kinase C

Parafollicular (PF) cells secrete 5-HT in response to stimulation of a G-protein-coupled Ca(2+) receptor (CaR) by increased extracellular Ca(2+)(↑[Ca(2+)](e)). We tested the hypothesis that protein kinase C (PKC) participates in stimulus–secretion coupling. Immunoblots from membrane and cytosolic fr...

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Bibliographic Details
Published in:J Neurosci
Main Authors: Liu, Kuo-peing, Hsiung, Shu-chi, Adlersberg, Mella, Sacktor, Todd, Gershon, Michael D., Tamir, Hadassah
Format: Artigo
Language:Inglês
Published: Society for Neuroscience 2000
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ARTICLE
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6772377/
https://ncbi.nlm.nih.gov/pubmed/10662827
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.20-04-01365.2000
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