Increased Binding Activity at an Antioxidant-Responsive Element in the Metallothionein-1 Promoter and Rapid Induction of Metallothionein-1 and -2 in Response to Cerebral Ischemia and Reperfusion

Metallothioneins (MTs) are cysteine-rich metal-binding proteins that are potentially involved in zinc homeostasis and free radical scavenging. The expression pattern of MT-1 and the binding activity of various MT-1 promoter elements were investigated after mild focal cerebral ischemia in the rat. Tr...

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Bibliografische gegevens
Gepubliceerd in:J Neurosci
Hoofdauteurs: Campagne, Menno van Lookeren, Thibodeaux, Harold, van Bruggen, Nick, Cairns, Belinda, Lowe, David G.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Society for Neuroscience 2000
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6772313/
https://ncbi.nlm.nih.gov/pubmed/10884303
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.20-14-05200.2000
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