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Circulating Insulin-Like Growth Factor I Mediates Effects of Exercise on the Brain

Physical exercise increases brain activity through mechanisms not yet known. We now report that in rats, running induces uptake of blood insulin-like growth factor I (IGF-I) by specific groups of neurons throughout the brain. Neurons accumulating IGF-I show increased spontaneous firing and a protrac...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Carro, Eva, Nuñez, Angel, Busiguina, Svetlana, Torres-Aleman, Ignacio
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2000
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6772191/
https://ncbi.nlm.nih.gov/pubmed/10751445
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.20-08-02926.2000
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