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Major drug resistance mutations to HIV-1 protease inhibitors (PI) among patients exposed to PI class failing antiretroviral therapy in São Paulo State, Brazil

BACKGROUND: Protease inhibitors (PI) are especially important in salvage therapy. Previous treatment failure with a PI containing regimen may elicit resistance mutations, reducing PI susceptibility and limiting treatment options. The aim of this study was to describe major PI mutations among patient...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Soldi, Giselle de Faria Romero, Ribeiro, Isadora Coutinho, Ahagon, Cintia Mayumi, Coelho, Luana Portes Ozório, Cabral, Gabriela Bastos, Lopes, Giselle Ibette Silva López, Ferreira, João Leandro de Paula, Brígido, Luís Fernando de Macedo
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6772045/
https://ncbi.nlm.nih.gov/pubmed/31574109
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0223210
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