Dysfunction of the blood-brain barrier in postoperative delirium patients, referring to the axonal damage biomarker phosphorylated neurofilament heavy subunit

BACKGROUND: Delirium is the most common postoperative complication of the central nervous system (CNS) that can trigger long-term cognitive impairment. Its underlying mechanism is not fully understood, but the dysfunction of the blood-brain barrier (BBB) has been implicated. The serum levels of the...

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Vydáno v:PLoS One
Hlavní autoři: Mietani, Kazuhito, Sumitani, Masahiko, Ogata, Toru, Shimojo, Nobutake, Inoue, Reo, Abe, Hiroaki, Kawamura, Gaku, Yamada, Yoshitsugu
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2019
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6771997/
https://ncbi.nlm.nih.gov/pubmed/31574089
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0222721
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