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Evolving generalists in switching rugged landscapes

Evolving systems, be it an antibody repertoire in the face of mutating pathogens or a microbial population exposed to varied antibiotics, constantly search for adaptive solutions in time-varying fitness landscapes. Generalists refer to genotypes that remain fit across diverse selective pressures; wh...

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Bibliografische gegevens
Gepubliceerd in:PLoS Comput Biol
Hoofdauteurs: Wang, Shenshen, Dai, Lei
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2019
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6771975/
https://ncbi.nlm.nih.gov/pubmed/31574088
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1007320
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