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Abscopal effect when combining oncolytic adenovirus and checkpoint inhibitor in a humanized NOG mouse model of melanoma

Melanoma, an immunogenic tumor, is the first indication where oncolytic viruses are now becoming part of clinical practice. ONCOS‐102, a transgened adenovirus, has shown to act as a primer of relevant tumor targeting immune cells both in preclinical and clinical melanoma studies. Strategies to augme...

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Detalhes bibliográficos
Publicado no:J Med Virol
Main Authors: Kuryk, Lukasz, Møller, Anne‐Sophie W., Jaderberg, Magnus
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6771875/
https://ncbi.nlm.nih.gov/pubmed/31081549
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jmv.25501
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