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Incorporating and interpreting regulatory guidance on estimands in diabetes clinical trials: The PIONEER 1 randomized clinical trial as an example

Regulatory guidelines describe the use of estimands in designing and conducting clinical trials. Estimands ensure alignment of the objectives with the design, conduct and analysis of a trial. An estimand is defined by four inter‐related attributes: the population of interest, the variable (endpoint)...

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Detalhes bibliográficos
Publicado no:Diabetes Obes Metab
Principais autores: Aroda, Vanita R., Saugstrup, Trine, Buse, John B., Donsmark, Morten, Zacho, Jeppe, Davies, Melanie J.
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6771751/
https://ncbi.nlm.nih.gov/pubmed/31168921
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/dom.13804
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