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The Impact of Alkyl‐Chain Purity on Lipid‐Based Nucleic Acid Delivery Systems – Is the Utilization of Lipid Components with Technical Grade Justified?

The physicochemical properties and transfection efficacies of two samples of a cationic lipid have been investigated and compared in 2D (monolayers at the air/liquid interface) and 3D (aqueous bulk dispersions) model systems using different techniques. The samples differ only in their chain composit...

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Detalhes bibliográficos
Publicado no:Chemphyschem
Main Authors: Pawlowska, Dorota, Janich, Christopher, Langner, Andreas, Dobner, Bodo, Wölk, Christian, Brezesinski, Gerald
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6771585/
https://ncbi.nlm.nih.gov/pubmed/31265754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cphc.201900480
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