Oncolytic Herpes Simplex Virus Immunotherapy for Brain Tumors: Current Pitfalls and Emerging Strategies to Overcome Therapeutic Resistance

Malignant tumors of the central nervous system (CNS) continue to be a leading cause of cancer-related mortality in both children and adults. Traditional therapies for malignant brain tumors consist of surgical resection and adjuvant chemoradiation; such approaches are often associated with extreme m...

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Detalhes bibliográficos
Publicado no:Oncogene
Main Authors: Totsch, Stacie K., Schlappi, Charles, Kang, Kyung-Don, Ishizuka, Andrew S., Lynn, Geoffrey M., Fox, Brandon, Beierle, Elizabeth A., Whitley, Richard J, Markert, James M., Gillespie, G. Yancey, Bernstock, Joshua D., Friedman, Gregory K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6771414/
https://ncbi.nlm.nih.gov/pubmed/31289361
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41388-019-0870-y
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