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Pedigree-based estimation of human mobile element retrotransposition rates

Germline mutation rates in humans have been estimated for a variety of mutation types, including single-nucleotide and large structural variants. Here, we directly measure the germline retrotransposition rate for the three active retrotransposon elements: L1, Alu, and SVA. We used three tools for ca...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Genome Res
Hauptverfasser: Feusier, Julie, Watkins, W. Scott, Thomas, Jainy, Farrell, Andrew, Witherspoon, David J., Baird, Lisa, Ha, Hongseok, Xing, Jinchuan, Jorde, Lynn B.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Cold Spring Harbor Laboratory Press 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6771411/
https://ncbi.nlm.nih.gov/pubmed/31575651
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.247965.118
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