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Circulating DNA as prognostic biomarker in patients with advanced hepatocellular carcinoma: a translational exploratory study from the SORAMIC trial

BACKGROUND: Liquid biopsy based on cell-free DNA circulating in plasma has shown solid results as a non-invasive biomarker. In the present study we evaluated the utility of circulating free DNA (cfDNA) and the sub-type tumor DNA (ctDNA) in hepatocellular cancer (HCC) patients to assess therapy respo...

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Pubblicato in:J Transl Med
Autori principali: Alunni-Fabbroni, Marianna, Rönsch, Kerstin, Huber, Thomas, Cyran, Clemens C., Seidensticker, Max, Mayerle, Julia, Pech, Maciej, Basu, Bristi, Verslype, Chris, Benckert, Julia, Malfertheiner, Peter, Ricke, Jens
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6771167/
https://ncbi.nlm.nih.gov/pubmed/31570105
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-019-2079-9
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