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Tumor‐Selective Altered Glycosylation and Functional Attenuation of CD73 in Human Hepatocellular Carcinoma

CD73, a cell‐surface N‐linked glycoprotein that produces extracellular adenosine, is a novel target for cancer immunotherapy. Although anti‐CD73 antibodies have entered clinical development, CD73 has both protumor and antitumor functions, depending on the target cell and tumor type. The aim of this...

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Detalhes bibliográficos
Publicado no:Hepatol Commun
Main Authors: Alcedo, Karel P., Guerrero, Andres, Basrur, Venkatesha, Fu, Dong, Richardson, Monea L., McLane, Joshua S., Tsou, Chih‐Chiang, Nesvizhskii, Alexey I., Welling, Theodore H., Lebrilla, Carlito B., Otey, Carol A., Kim, Hong Jin, Omary, M. Bishr, Snider, Natasha T.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6771166/
https://ncbi.nlm.nih.gov/pubmed/31592495
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep4.1410
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