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Gene Co-Expression Networks Restructured Gene Fusion in Rhabdomyosarcoma Cancers
Rhabdomyosarcoma is subclassified by the presence or absence of a recurrent chromosome translocation that fuses the FOXO1 and PAX3 or PAX7 genes. The fusion protein (FOXO1-PAX3/7) retains both binding domains and becomes a novel and potent transcriptional regulator in rhabdomyosarcoma subtypes. Many...
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| Publicado no: | Genes (Basel) |
|---|---|
| Main Authors: | , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
MDPI
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6770752/ https://ncbi.nlm.nih.gov/pubmed/31480361 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/genes10090665 |
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