Avian Expression Patterns and Genomic Mapping Implicate Leptin in Digestion and TNF in Immunity, Suggesting That Their Interacting Adipokine Role Has Been Acquired Only in Mammals

In mammals, leptin and tumor-necrosis factor (TNF) are prominent interacting adipokines mediating appetite control and insulin sensitivity. While TNF pleiotropically functions in immune defense and cell survival, leptin is largely confined to signaling energy stores in adipocytes. Knowledge about th...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Seroussi, Eyal, Knytl, Martin, Pitel, Frédérique, Elleder, Daniel, Krylov, Vladimir, Leroux, Sophie, Morisson, Mireille, Yosefi, Sara, Miyara, Shoval, Ganesan, Saibaba, Ruzal, Mark, Andersson, Leif, Friedman-Einat, Miriam
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6770569/
https://ncbi.nlm.nih.gov/pubmed/31514326
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20184489
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