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Downregulation of POFUT1 Impairs Secondary Myogenic Fusion Through a Reduced NFATc2/IL-4 Signaling Pathway

Past work has shown that the protein O-fucosyltransferase 1 (POFUT1) is involved in mammal myogenic differentiation program. Pofut1 knockdown (Po –) in murine C2C12 cells leads to numerous elongated and thin myotubes, suggesting significant defects in secondary fusion. Among the few pathways involve...

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Bibliografske podrobnosti
izdano v:Int J Mol Sci
Main Authors: Der Vartanian, Audrey, Chabanais, Julien, Carrion, Claire, Maftah, Abderrahman, Germot, Agnès
Format: Artigo
Jezik:Inglês
Izdano: MDPI 2019
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6770550/
https://ncbi.nlm.nih.gov/pubmed/31500188
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20184396
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