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Targeting of CD133+ Cancer Stem Cells by Mesenchymal Stem Cell Expressing TRAIL Reveals a Prospective Role of Apoptotic Gene Regulation in Non-Small Cell Lung Cancer

Mesenchymal stem cells (MSCs) are emerging as vehicles for anti-tumor cytotherapy; however, investigation on its efficacy to target a specific cancer stem cell (CSC) population in non-small cell lung cancer (NSCLC) is lacking. Using assays to evaluate cell proliferation, apoptosis, and gene expressi...

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Detalhes bibliográficos
Publicado no:Cancers (Basel)
Main Authors: Shaik Fakiruddin, Kamal, Lim, Moon Nian, Nordin, Norshariza, Rosli, Rozita, Zakaria, Zubaidah, Abdullah, Syahril
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6770521/
https://ncbi.nlm.nih.gov/pubmed/31466290
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers11091261
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