Elevated H2AX Phosphorylation Observed with kINPen Plasma Treatment Is Not Caused by ROS-Mediated DNA Damage but Is the Consequence of Apoptosis

Phosphorylated histone 2AX (γH2AX) is a long-standing marker for DNA double-strand breaks (DSBs) from ionizing radiation in the field of radiobiology. This led to the perception of γH2AX being a general marker of direct DNA damage with the treatment of other agents such as low-dose exogenous ROS tha...

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Dettagli Bibliografici
Pubblicato in:Oxid Med Cell Longev
Autori principali: Bekeschus, Sander, Schütz, Clarissa S., Nießner, Felix, Wende, Kristian, Weltmann, Klaus-Dieter, Gelbrich, Nadine, von Woedtke, Thomas, Schmidt, Anke, Stope, Matthias B.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Hindawi 2019
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6770374/
https://ncbi.nlm.nih.gov/pubmed/31641425
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2019/8535163
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