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Current and Future Horizons of Patient-Derived Xenograft Models in Colorectal Cancer Translational Research

Our poor understanding of the intricate biology of cancer and the limited availability of preclinical models that faithfully recapitulate the complexity of tumors are primary contributors to the high failure rate of novel therapeutics in oncology clinical studies. To address this need, patient-deriv...

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Detalhes bibliográficos
Publicado no:Cancers (Basel)
Main Authors: Inoue, Akira, Deem, Angela K., Kopetz, Scott, Heffernan, Timothy P., Draetta, Giulio F., Carugo, Alessandro
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6770280/
https://ncbi.nlm.nih.gov/pubmed/31500168
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers11091321
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