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Regulatory Effects and Interactions of the Wnt and OPG-RANKL-RANK Signaling at the Bone-Cartilage Interface in Osteoarthritis

Cartilage and the bordering subchondral bone form a functionally active regulatory interface with a prominent role in osteoarthritis pathways. The Wnt and the OPG-RANKL-RANK signaling systems, as key mediators, interact in subchondral bone remodeling. Osteoarthritic osteoblasts polarize into two dis...

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Bibliografski detalji
Izdano u:Int J Mol Sci
Glavni autori: Kovács, Béla, Vajda, Enikő, Nagy, Előd Ernő
Format: Artigo
Jezik:Inglês
Izdano: MDPI 2019
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6769977/
https://ncbi.nlm.nih.gov/pubmed/31546898
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20184653
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