Inhibition of Tyrosine-Phosphorylated STAT3 in Human Breast and Lung Cancer Cells by Manuka Honey is Mediated by Selective Antagonism of the IL-6 Receptor

Aberrantly high levels of tyrosine-phosphorylated signal transducer and activator of transcription 3 (p-STAT3) are found constitutively in ~50% of human lung and breast cancers, acting as an oncogenic transcription factor. We previously demonstrated that Manuka honey (MH) inhibits p-STAT3 in breast...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Aryappalli, Priyanka, Shabbiri, Khadija, Masad, Razan J., Al-Marri, Roadha H., Haneefa, Shoja M., Mohamed, Yassir A., Arafat, Kholoud, Attoub, Samir, Cabral-Marques, Otavio, Ramadi, Khalil B., Fernandez-Cabezudo, Maria J., al-Ramadi, Basel K.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6769459/
https://ncbi.nlm.nih.gov/pubmed/31491838
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20184340
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