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Robust synchronization of the cell cycle and the circadian clock through bidirectional coupling

The cell cycle and the circadian clock represent major cellular rhythms, which appear to be coupled. Thus the circadian factor BMAL1 controls the level of cell cycle proteins such as Cyclin E and WEE1, the latter of which inhibits the kinase CDK1 that governs the G2/M transition. In reverse the cell...

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Sonraí Bibleagrafaíochta
Foilsithe in:J R Soc Interface
Main Authors: Yan, Jie, Goldbeter, Albert
Formáid: Artigo
Teanga:Inglês
Foilsithe: The Royal Society 2019
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6769306/
https://ncbi.nlm.nih.gov/pubmed/31506042
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsif.2019.0376
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