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Amphiphilic nanogels: influence of surface hydrophobicity on protein corona, biocompatibility and cellular uptake

BACKGROUND AND PURPOSE: Nanogels (NGs) are promising drug delivery tools but are typically limited to hydrophilic drugs. Many potential new drugs are hydrophobic. Our study systematically investigates amphiphilic NGs with varying hydrophobicity, but similar colloidal features to ensure comparability...

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Detalhes bibliográficos
Publicado no:Int J Nanomedicine
Main Authors: Bewersdorff, Tony, Gruber, Alexandra, Eravci, Murat, Dumbani, Malti, Klinger, Daniel, Haase, Andrea
Formato: Artigo
Idioma:Inglês
Publicado em: Dove 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6769055/
https://ncbi.nlm.nih.gov/pubmed/31576128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S215935
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