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Destruction of tumor mass by gadolinium-loaded nanoparticles irradiated with monochromatic X-rays: Implications for the Auger therapy

Synchrotron generated monochromatic X-rays can be precisely tuned to the K-shell energy of high Z materials resulting in the release of the Auger electrons. In this work, we have employed this mechanism to destruct tumor spheroids. We first loaded gadolinium onto the surface of mesoporous silica nan...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Matsumoto, Kotaro, Saitoh, Hiroyuki, Doan, Tan Le Hoang, Shiro, Ayumi, Nakai, Keigo, Komatsu, Aoi, Tsujimoto, Masahiko, Yasuda, Ryo, Kawachi, Tetsuya, Tajima, Toshiki, Tamanoi, Fuyuhiko
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6768997/
https://ncbi.nlm.nih.gov/pubmed/31570738
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-49978-1
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