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The structural basis for RNA selectivity by the IMP family of RNA-binding proteins

The IGF2 mRNA-binding proteins (ZBP1/IMP1, IMP2, IMP3) are highly conserved post-transcriptional regulators of RNA stability, localization and translation. They play important roles in cell migration, neural development, metabolism and cancer cell survival. The knockout phenotypes of individual IMP...

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Detalles Bibliográficos
Publicado en:Nat Commun
Main Authors: Biswas, Jeetayu, Patel, Vivek L., Bhaskar, Varun, Chao, Jeffrey A., Singer, Robert H., Eliscovich, Carolina
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group UK 2019
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6768852/
https://ncbi.nlm.nih.gov/pubmed/31570709
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-12193-7
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