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The small molecule nitazoxanide selectively disrupts BAM-mediated folding of the outer membrane usher protein
Bacterial pathogens assemble adhesive surface structures termed pili or fimbriae to initiate and sustain infection of host tissues. Uropathogenic Escherichia coli, the primary causative agent of urinary tract infections, expresses type 1 and P pili required for colonization of the bladder and kidney...
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| Publicado no: | J Biol Chem |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6768635/ https://ncbi.nlm.nih.gov/pubmed/31391254 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.009616 |
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