Targeted in-vitro-stimulation reveals highly proliferative multi-virus-specific human central memory T cells as candidates for prophylactic T cell therapy

Adoptive T cell therapy (ACT) has become a treatment option for viral reactivations in patients undergoing allogeneic hematopoietic stem cell transplantation (alloHSCT). Animal models have shown that pathogen-specific central memory T cells (T(CM)) are protective even at low numbers and show long-te...

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Опубликовано в: :PLoS One
Главные авторы: Faist, Benjamin, Schlott, Fabian, Stemberger, Christian, Dennehy, Kevin M., Krackhardt, Angela, Verbeek, Mareike, Grigoleit, Götz U., Schiemann, Matthias, Hoffmann, Dieter, Dick, Andrea, Martin, Klaus, Hildebrandt, Martin, Busch, Dirk H., Neuenhahn, Michael
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2019
Предметы:
Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6768573/
https://ncbi.nlm.nih.gov/pubmed/31568490
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0223258
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