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Synthesis, crystal structure, DFT studies and biological activity of (Z)-3-(3-bromophenyl)-1-(1,5-dimethyl-1H-pyrazol-3-yl)-3-hydroxyprop-2-en-1-one

BACKGROUND: Nowadays, is emerging a new generation of highly promising inhibitors bearing the β-ketoenol functionality. The present work relates to the first synthesis, the structure determination, the DFT studies and the use of a new biomolecule designed with a β-ketoenol group bounded to a pyrazol...

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Detalhes bibliográficos
Publicado no:Chem Cent J
Main Authors: Tighadouini, Said, Benabbes, Redouane, Tillard, Monique, Eddike, Driss, Haboubi, Khadija, Karrouchi, Khalid, Radi, Smaail
Formato: Artigo
Idioma:Inglês
Publicado em: Springer International Publishing 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6768133/
https://ncbi.nlm.nih.gov/pubmed/30474759
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13065-018-0492-4
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