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What Have We Learned from Studies of IFN-λ Variants and Hepatitis C Virus Infection?

Chronic infection with the hepatitis C virus (HCV) is a major cause of cirrhosis and hepatocellular carcinoma. In 2009, genome-wide association studies (GWAS) strongly linked genetic variants in the interferon lambda (IFN-λ) chromosomal region to HCV clearance. In 2013, discovery of the IFNL4 gene p...

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Detalhes bibliográficos
Publicado no:J Interferon Cytokine Res
Main Authors: O'Brien, Thomas R., Jackson, Sarah S.
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc., publishers 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6767860/
https://ncbi.nlm.nih.gov/pubmed/31161939
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/jir.2019.0048
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