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What Have We Learned from Studies of IFN-λ Variants and Hepatitis C Virus Infection?
Chronic infection with the hepatitis C virus (HCV) is a major cause of cirrhosis and hepatocellular carcinoma. In 2009, genome-wide association studies (GWAS) strongly linked genetic variants in the interferon lambda (IFN-λ) chromosomal region to HCV clearance. In 2013, discovery of the IFNL4 gene p...
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| Pubblicato in: | J Interferon Cytokine Res |
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| Autori principali: | , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Mary Ann Liebert, Inc., publishers
2019
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6767860/ https://ncbi.nlm.nih.gov/pubmed/31161939 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/jir.2019.0048 |
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