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Dapsone‐ and nitroso dapsone‐specific activation of T cells from hypersensitive patients expressing the risk allele HLA‐B*13:01

BACKGROUND: Research into drug hypersensitivity associated with the expression of specific HLA alleles has focussed on the interaction between parent drug and the HLA with no attention given to reactive metabolites. For this reason, we have studied HLA‐B*13:01‐linked dapsone hypersensitivity to (a)...

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Publicado en:Allergy
Autores principales: Zhao, Qing, Alhilali, Khetam, Alzahrani, Abdulaziz, Almutairi, Mubarak, Amjad, Juwaria, Liu, Hong, Sun, Yonghu, Sun, Lele, Zhang, Huimin, Meng, Xiaoli, Gibson, Andrew, Ogese, Monday O., Kevin Park, B., Liu, Jianjun, Ostrov, David A., Zhang, Furen, Naisbitt, Dean J.
Formato: Artigo
Lenguaje:Inglês
Publicado: John Wiley and Sons Inc. 2019
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6767778/
https://ncbi.nlm.nih.gov/pubmed/30844087
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/all.13769
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