Dynamic clamping human and rabbit atrial calcium current: narrowing I (CaL) window abolishes early afterdepolarizations

KEY POINTS: Early‐afterdepolarizations (EADs) are abnormal action potential oscillations and a known cause of cardiac arrhythmias. Ventricular EADs involve reactivation of a Ca(2+) current (I (CaL)) in its ‘window region’ voltage range. However, electrical mechanisms of atrial EADs, a potential caus...

Full description

Saved in:
Bibliographic Details
Published in:J Physiol
Main Authors: Kettlewell, Sarah, Saxena, Priyanka, Dempster, John, Colman, Michael A., Myles, Rachel C., Smith, Godfrey L., Workman, Antony J.
Format: Artigo
Language:Inglês
Published: John Wiley and Sons Inc. 2019
Subjects:
Cardiovascular
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6767690/
https://ncbi.nlm.nih.gov/pubmed/31093979
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/JP277827
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items