miR-145 sensitizes esophageal squamous cell carcinoma to cisplatin through directly inhibiting PI3K/AKT signaling pathway

BACKGROUND: Esophageal squamous cell carcinoma (ESCC) is the eighth most common cancer worldwide and is one of the most lethal malignancies. Cisplatin (DDP) is a key drug for ESCC treatment, but the presence of chemotherapy resistance limits the use of DDP. To enhance chemosensitivity to DDP is impo...

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Udgivet i:Cancer Cell Int
Main Authors: Zheng, Tian-Liang, Li, De-Ping, He, Zhan-Feng, Zhao, Song
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2019
Fag:
Primary Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6767650/
https://ncbi.nlm.nih.gov/pubmed/31582906
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12935-019-0943-6
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