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Reviewing HIV-1 Gag Mutations in Protease Inhibitors Resistance: Insights for Possible Novel Gag Inhibitor Designs

HIV protease inhibitors against the viral protease are often hampered by drug resistance mutations in protease and in the viral substrate Gag. To overcome this drug resistance and inhibit viral maturation, targeting Gag alongside protease rather than targeting protease alone may be more efficient. I...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Su, Chinh Tran-To, Koh, Darius Wen-Shuo, Gan, Samuel Ken-En
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6767625/
https://ncbi.nlm.nih.gov/pubmed/31489889
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules24183243
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