Recently Registered Midazolam Doses for Preterm Neonates Do Not Lead to Equal Exposure: A Population Pharmacokinetic Model

Although midazolam is a frequently used sedative in neonatal intensive care units, its use in preterm neonates has been off‐label. Recently, a new dosing advice for midazolam for sedation on intensive care units has been included in the label (0.03 mg/[kg·h] for preterm neonates <32 weeks and 0.0...

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Udgivet i:J Clin Pharmacol
Main Authors: Völler, Swantje, Flint, Robert B., Beggah, Fouzi, Reiss, Irwin, Andriessen, Peter, Zimmermann, Luc J.I., van den Anker, John N., Liem, Kian D., Koch, Birgit C.P., de Wildt, Saskia, Knibbe, Catherijne A.J., Simons, Sinno H.P.
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2019
Fag:
Pediatric Pharmacology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6767398/
https://ncbi.nlm.nih.gov/pubmed/31093992
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcph.1429
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