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Understanding Vision Loss from Optic Pathway Glioma in Neurofibromatosis Type 1

Neurofibromatosis type 1 (NF1) is a common cancer predisposition syndrome caused by mutations in the NF1 gene. The NF1-encoded protein (neurofibromin) functions as an inhibitor of RAS to control cell growth and survival. Individuals with NF1 are prone to developing low-grade tumors of the optic nerv...

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Detalles Bibliográficos
Publicado en:J Neurosci Res
Main Authors: Freret, Morgan E., Gutmann, David H.
Formato: Artigo
Idioma:Inglês
Publicado: 2018
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6766750/
https://ncbi.nlm.nih.gov/pubmed/29704429
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jnr.24250
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