Interleukin-1 receptor accessory proteins are required for normal homeostatic responses to sleep deprivation

Interleukin-1β (IL1) is a sleep regulatory substance. The IL1/IL1 type 1 receptor complex requires a receptor accessory protein (AcP) to signal. There are three isoforms of AcP. In the current experiments, mice lacking a neuron-specific isoform, called AcPb knockout (AcPb KO), or mice lacking AcP +...

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Veröffentlicht in:J Appl Physiol (1985)
Hauptverfasser: Nguyen, Joseph, Gibbons, Cody M., Dykstra-Aiello, Cheryl, Ellingsen, Riley, Koh, Khia Min Sabrina, Taishi, Ping, Krueger, James M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Physiological Society 2019
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6766708/
https://ncbi.nlm.nih.gov/pubmed/31295066
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/japplphysiol.00366.2019
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