Macrophage-derived insulin-like growth factor-1 is a key neurotrophic and nerve-sensitizing factor in pain associated with endometriosis

Endometriosis is a common incurable inflammatory disorder that is associated with debilitating pelvic pain in women. Macrophages are central to the pathophysiology of endometriosis: they dictate the growth and vascularization of endometriosis lesions and more recently have been shown to promote lesi...

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Publicado en:FASEB J
Autores principales: Forster, Rachel, Sarginson, Alexandra, Velichkova, Atanaska, Hogg, Chloe, Dorning, Ashley, Horne, Andrew W., Saunders, Philippa T. K., Greaves, Erin
Formato: Artigo
Lenguaje:Inglês
Publicado: Federation of American Societies for Experimental Biology 2019
Materias:
Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6766660/
https://ncbi.nlm.nih.gov/pubmed/31291762
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.201900797R
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