Protective effects of GPR37 via regulation of inflammation and multiple cell death pathways after ischemic stroke in mice

GPCR 37 (GPR37) is a GPCR expressed in the CNS; its physiological and pathophysiological functions are largely unknown. We tested the role of GPR37 in the ischemic brain of GPR37 knockout (KO) mice, exploring the idea that GPR37 might be protective against ischemic damage. In an ischemic stroke mode...

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Foilsithe in:FASEB J
Main Authors: McCrary, Myles R., Jiang, Michael Q., Giddens, Michelle M., Zhang, James Y., Owino, Sharon, Wei, Zheng Z., Zhong, Weiwei, Gu, Xiaohuan, Xin, Huang, Hall, Randy A., Wei, Ling, Yu, Shan P.
Formáid: Artigo
Teanga:Inglês
Foilsithe: Federation of American Societies for Experimental Biology 2019
Ábhair:
Research
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6766648/
https://ncbi.nlm.nih.gov/pubmed/31268736
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.201900070R
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