Paclitaxel alleviated sepsis-induced acute lung injury by activating MUC1 and suppressing TLR-4/NF-κB pathway

PURPOSE: It has been reported that approximately 40% of ALI (acute lung injury) incidence resulted from sepsis. Paclitaxel, as a classic anti-cancer drug, plays an important role in the regulation of inflammation. However, we do not know whether it has a protective effect against CLP (cecal ligation...

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Udgivet i:Drug Des Devel Ther
Main Authors: Wang, Yu-Ming, Ji, Ran, Chen, Wei-Wei, Huang, Shun-Wei, Zheng, Yan-Jun, Yang, Zhi-Tao, Qu, Hong-Ping, Chen, Hao, Mao, En-Qiang, Chen, Ying, Chen, Er-Zhen
Format: Artigo
Sprog:Inglês
Udgivet: Dove 2019
Fag:
Original Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6766586/
https://ncbi.nlm.nih.gov/pubmed/31576113
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S222296
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