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Progestin Therapy to Prevent Preterm Birth: History and Effectiveness of Current Strategies and Development of Novel Approaches

In the 1930s the “progestin” hormone produced by the corpus luteum was isolated and found to be a Δ(4)-keto-steroid. It was aptly named progesterone (P4) and in the following 30 years the capacity of P4 and derivatives to prevent preterm birth (PTB) was examined. Outcomes of multiple small studies s...

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Detalhes bibliográficos
Publicado no:Placenta
Main Authors: Mesiano, Sam A, Peters, Gregory A, Amini, Peyvand, Wilson, Rachel A, Tochtrop, Gregory P, van Den Akker, Focco
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6766339/
https://ncbi.nlm.nih.gov/pubmed/30745115
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.placenta.2019.01.018
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